Philip Eaton Selected Research

Hypertrophy

11/2020	Mitochondrial pyruvate carrier abundance mediates pathological cardiac hypertrophy.
1/2019	Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension.
1/2017	Examining a role for PKG Iα oxidation in the pathogenesis of cardiovascular dysfunction during diet-induced obesity.

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Philip Eaton Research Topics

Disease

10	Ischemia 01/2021 - 03/2002
6	Hypertension (High Blood Pressure) 01/2022 - 01/2012
5	Hypoxia (Hypoxemia) 01/2020 - 09/2007
4	Neoplasms (Cancer) 11/2023 - 01/2020
4	Inflammation (Inflammations) 01/2022 - 01/2019
4	Heart Failure 01/2021 - 09/2012
3	Reperfusion Injury 11/2023 - 09/2010
3	Myocardial Ischemia (Ischemic Heart Diseases) 11/2023 - 01/2018
3	Sepsis (Septicemia) 01/2022 - 08/2011
3	Infarction (Infarctions) 01/2021 - 09/2010
3	Hypertrophy 11/2020 - 01/2017
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 06/2008
2	Pulmonary Arterial Hypertension 12/2023 - 01/2019
2	Cardiotoxicity 11/2023 - 12/2016
2	Cardiomegaly (Heart Hypertrophy) 11/2020 - 08/2012
2	Obesity 01/2019 - 01/2017
2	Pain (Aches) 01/2019 - 10/2014
2	Disease Progression 10/2018 - 11/2013
2	Cardiomyopathies (Cardiomyopathy) 12/2016 - 01/2016
1	Vascular Remodeling 12/2023
1	Myocardial Infarction 11/2023
1	Colitis 11/2022
1	Genomic Instability 01/2022
1	Body Weight (Weight, Body) 01/2022
1	Carcinogenesis 01/2022
1	Lewis Lung Carcinoma 01/2020
1	Fibrosis (Cirrhosis) 01/2019
1	Insulin Resistance 01/2019
1	Heart Diseases (Heart Disease) 10/2018

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2002
7	DisulfidesIBA 12/2023 - 10/2004
6	Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA 11/2021 - 01/2012
4	Cysteine (L-Cysteine)FDA Link 11/2022 - 08/2003
4	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 11/2021 - 10/2004
4	Oxygen (Dioxygen)IBA 01/2019 - 09/2007
4	Oxidants (Oxidizing Agents)IBA 10/2014 - 03/2003
3	Angiotensin IIIBA 01/2022 - 06/2014
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2022 - 08/2011
3	Monocarboxylic Acid TransportersIBA 01/2021 - 01/2016
3	Epoxide HydrolasesIBA 01/2020 - 06/2014
3	HydrolasesIBA 01/2020 - 02/2011
3	AntioxidantsIBA 10/2018 - 07/2005
3	Biotin (Vitamin H)FDA Link 08/2011 - 08/2003
2	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2023 - 01/2019
2	CalciumIBA 01/2021 - 01/2019
2	Protein Isoforms (Isoforms)IBA 01/2019 - 06/2011
2	Oxidoreductases (Dehydrogenase)IBA 01/2019 - 11/2002
2	EnzymesIBA 01/2019 - 01/2004
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2019 - 06/2014
2	Superoxides (Superoxide)IBA 01/2017 - 08/2011
2	Sulfhydryl Compounds (Thiols)IBA 01/2017 - 11/2002
2	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2016 - 10/2004
2	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 12/2016 - 08/2012
2	Protein SIBA 08/2011 - 08/2003
2	phospholemmanIBA 09/2010 - 01/2004
2	Adenosine Triphosphatases (ATPase)IBA 01/2004 - 03/2003
1	Auranofin (Ridaura)FDA Link 12/2023
1	CyclinsIBA 12/2023
1	purinoceptor P2Y6IBA 11/2022
1	Serine (L-Serine)FDA Link 11/2022
1	DNA Transposable Elements (Element, IS)IBA 01/2022
1	Retroelements (Retrotransposon)IBA 01/2022
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	Tryptophan (L-Tryptophan)FDA Link 11/2021
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 11/2021
1	Pyruvic Acid (Pyruvate)IBA 01/2021
1	1- (3- ((4- (2- fluorophenyl)piperazin- 1- yl)methyl)- 4- methoxyphenyl)- 2,3,4,9- tetrahydro- 1H- pyrido(3,4- b)indole- 3- carboxylic acidIBA 01/2021
1	Two-Pore ChannelsIBA 01/2021
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2021
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2021
1	Tamoxifen FDA LinkGeneric 11/2020
1	NitritesIBA 01/2020
1	Alkenes (Olefins)IBA 01/2020
1	AcidsIBA 01/2020
1	Oleic Acid (Oleate)IBA 01/2020
1	UbiquinoneIBA 01/2019
1	polysulfideIBA 01/2019
1	CystathionineIBA 01/2019
1	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 01/2019
1	Ion Channels (Ion Channel)IBA 01/2019
1	Iron-Sulfur ProteinsIBA 01/2019
1	LyasesIBA 01/2019
1	NAD (NADH)IBA 01/2019
1	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 01/2019
1	RotenoneIBA 01/2019
1	Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA 01/2019
1	Reducing AgentsIBA 01/2019
1	Small Interfering RNA (siRNA)IBA 01/2019
1	Contractile ProteinsIBA 10/2018
1	Myosins (Myosin)IBA 10/2018
1	Mitogen-Activated Protein Kinase 14IBA 01/2018
1	Nitric Oxide Synthase (NO Synthase)IBA 01/2017
1	Glucagon (Glukagon)FDA Link 01/2017
1	ResistinIBA 01/2017
1	LeptinIBA 01/2017
1	5-dehydro-3-deoxy-D-arabino-heptulosonic acid-7-phosphate (DAHP)IBA 01/2017

Therapy/Procedure

4	Therapeutics 11/2023 - 04/2011
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 11/2023
1	Percutaneous Coronary Intervention 11/2023